ALESSANDRO BERTERO, Ph.D

Dr. Alessandro Bertero is an Acting Assistant Professor in the Dept. of Laboratory Medicine & Pathology at the University of Washington in Seattle, USA. He is a faculty member of the Institute for Stem Cell and Regnenerative Medicine and the Center for Cardiovascular Biology. During his undergraduate studies he trained with the late Prof. Guido Tarone at the University of Turin in Italy, where he studied heart hypertrophy and obtained a BSci (2009) and an MSci (2011). Having being awarded a British Heart Foundation Graduate Fellowship, he joined the University of Cambridge in the UK where he obtained an MRes (2012) and a PhD (2016) by dissecting the mechanisms involved in the early differentiation of human pluripotent stem cells in the laboratory of Ludovic Vallier. Dr. Bertero performed his postdoctoral training with Prof. Charles Murry at the University of Washington with the support of an EMBO Long-Term Fellowship (2017). During this time he investigated the control of gene expression during cardiac development and in heart disease. Dr. Bertero became a junior faculty member in July 2019.

Dr. Bertero’s laboratory develops innovative approaches to manipulate gene, cell, and tissue function, and applies these advancements to provide a fresh take on key open questions in gene regulation, heart development, and heart disease. The lab is also exploring how their skillset may aid climate change mitigation by advancing the field of cellular agriculture. Dr. Bertero co-invented OPTiOX, a technology that enables the rapid, efficient, and cost-effective differentiation of pluripotent stem cells into differentiated cell types such as skeletal muscle. This approach is empowering the generation of human cells for drug discovery and regenerative medicine (bit.bio LTD) as well as animal cells for cultured meat (Meatable).

KEY EXPERTISE AREAS

  • Pluripotent stem cell culture and differentiation
  • Synthetic biology and genetic engineering
  • Cardiac muscle biology